Chronic pain is a major cause of disability worldwide with a prevalence rate of 15% to 30% in the general adult population, and more than 500 billion dollars annual costs in the United States. Lack of showing of satisfactory results with available pharmacotherapy; currently, opioids are the linchpin for pain control for most cases including, neuropathic and cancer pain. Nonetheless, it doesn't come as a surprise that the inherent adverse events of opioids are representing major concerns.
Cannabidiol (CBD) has gained significant popularity in the field of alternative medicine because it comes with the benefit of minimal to no side effects like the modern medicines. Although research is yet uncover the mechanism of action of health benefits CBD offer, studies conducted till date show that it is effective in managing pain. Ethan B. R., "Cannabinoids in the management of difficult to treat pain," Ther Clin Risk Manag. 2008 Feb; 4(1): 245–259.
National Academies of Science, Engineering, and Medicine conducted an extensive systematic review to evaluate cannabinoids, stating that there is ‘extensive evidence’ of cannabinoids’ efficacy in pain relief with good tolerability. Meng H, et al. Selective cannabinoids for chronic neuropathic pain: a systematic review and meta-analysis. Anesthesia Analg. 2017;125:1638–1652.
A recent study conducted by Vitamed Research LLC showed that among all participants who were 45.26±14.02 (Mean±SD) years old:
"63% report to have tried a CBD product (including products containing THC) and 37.30% of these answered that the used CBD product did not contain THC.
The majority responded that CBD products have helped their condition (57.45%) and reduced their pain medication (61.7%), including opioids (44.68%).
Among the pain conditions patients reported relieve were back pain (63.83%), nerve pain (38.30%), neck pain (38.30%), migraines (29.79%), limb pain (19.15%), fibromyalgia (19.15%), and other (19.15%).
Overall, participants familiarity with the dosing of their CBD product varied. Generally, participants believe CBD is a good treatment option, and not harmful. The overall attitude and experience of participants regarding CBD products was positive and CBD only was reported to reduce pain medication, including opioids." Moeller-Bertram T., (360) Can CBD Reduce the Use of Pain Medication? Lessons from a Survey in a Pain Clinic Environment. April 2019. Volume 20, Issue 4, Supplement, Page S64.
In addition to their potential direct effects on pain, cannabinoids are suggested to have a role in reducing opioid intake. Abrams D.I., The therapeutic effects of cannabis and cannabinoids: an update from the national academies of sciences, engineering and medicine report. Eur J Intern Med. 2018;49:7–11.
A study conducted by the Department of Public Administration and Policy at University of Georgia, Athens, concludes that cannabinoids use may mitigate the escalation of opioid doses in patients with chronic pain with a substantial reduction in opioid intake. Bradford A.C., et al. Association between US state medical cannabis laws and opioid prescribing in the medicare part D population. JAMA Intern Med. 2018;178:667–672.
Medicare prescriptions’ reports revealed reduced opioids’ use and their consequent adverse events in the United States (U.S.) with legalized cannabis access. Wiese B, and Wilson-Poe A.R., Emerging evidence for cannabis’ role in opioid use disorder. Cannabis Cannabinoid Res. 2018;3:179–189.
In addition, it was found that CBD reduced the craving, anxiety and psychological manifestations significantly in drug-abstinent individuals with previous opioid dependency. Hurd Y.L., et al. Cannabidiol for the reduction of cue-induced craving and anxiety in drug-abstinent individuals with heroin use disorder: a double-blind randomized placebo-controlled trial. Am J Psychiatry. 2019 May 21.
Although no studies to date have evaluated the effects of readily available hemp CBD in chronic pain and opioid use in a single cohort, emerging literature supports evidence for CBD in pain relief and opioid reduction.
The opioid epidemic continues to claim more and more lives on an everyday basis, finding alternative treatment options is more crucial than ever. Also, effective treatment options for opioid use disorder not currently available in the market. Given the recent studies with CBD and pain management, there is a high possibility that CBD may fill that gap.
However, it is important that you discuss with your physician or healthcare provider before using any CBD product(s). The side effects associated with CBD cannot be ignored. The US Food and Drug Administration (FDA) has repeatedly warned people to consult a physician or a healthcare provider before using CBD. Given that CBD industry is so large and fairly unregulated, it is fair to say that picking the right product for you is a daunting task.
Keeping the above factors and the product safety and efficacy - in addition to rapidly changing FDA regulations - at the forefront of our mission, we developed cannabidiol (CBD) formulations that are available to consumers only after a discussion with their physician or healthcare provider ("PHP"). We strongly encourage everyone to consult a PHP and learn about if and what CBD can do for you prior to using any CBD products. Our goal is to keep prevent people from taking CBD because "it is out there" and/or "it is available at a cheaper price." Contact us to learn more about our products.
Flower Petals Botanicals LLC does not sell or distribute any products that are in violation of the United States Controlled Substances Act (USA CDA). We do sell and distribute hemp-based products. We are committed to scientifically advanced products to better serve the community. Research over the years has shown that CBD can be beneficial to a healthy lifestyle and serve as a possible alternative to traditional medications for a range of ailments. If CBD oil could improve your mental or physical well-being, there is no better time than now to start using it. Contact a physician or healthcare provider near you and ask our products.